BPS Bioscience
- 服务名称:
BPS Bioscience的激酶筛选和检测服务
Accelerate your drug discovery program with Kinase Screening and Profiling Services from BPS Bioscience, Inc. Trust us to provide you with high quality data with fast turnaround time. Our team of experts along with our broad services portfolio makes it easy to:
Screen for inhibitors/targets using our unique panel of 75+ assays
Select from IC50 determination and single point concentrations
Receive data within days of compound submission
Perform follow-up studies using the same proteins manufactured in-house
Get questions answered or project guidance in a time-efficient manner
Biochemical Assays
Lipid:
PI3Kα (p110α/p85α) | PI3Kβ (p110β/p85α) | PI3Kδ (p110δ/p85α) | PI3Kγ (p110γ/PIK3R5) |
SPHK1 |
Tyrosine:
Abl | c-Src | FGFR3(V443M) | PDGFRα |
Abl-1 (T315I) | EGFR (WT) | FGFR4 | PDGFRα(D842Y) |
ALK | EGFR (L858R) | Flt1 | RET |
ALK2 | EGFR (T790M) | Flt3 | ROS1 |
AXL | EGFR (L858R, T790M) | FYN | SYK |
BTK | EGFR(T790M, C797S,L858R) | HER2 | TYK2 |
cKIT(D816V) | EGFR (murine) | HER4 | TYRO3 |
cKIT(V654A) | EphA2 | Jak1 | VEGFR2/KDR |
cMet | EphB4 | Jak2(JH2) | Yes1 |
cMet (exon 14 Del) | FAK | Jak2(JH2)(V617F) | |
cMet (WT) | FGFR2 | Jak3 | |
cMer | FGFR3(L496V) | FGFR2 | |
CSF1R(FMS) | FGFR3(V443L) | Lck |
Serine-Threonine:
AKT | CDK4/CyclinD1 | GSK3a | PIM2 |
Aurora A | CDK4/CyclinD3 | GSK3b | PIM3 |
BRAF | CDK5/p25 | HPK1/MAP4K1 | RIPK1 |
BRAF (V600E) | CDK6/CyclinD3 | IKKβ | RIPK2 |
Casein Kinase 1 | CDK7/CyclinH1/ MNET1 | MNK1 | TAK1-TAB1 |
CDK1/CyclinB1 | CDK9/CyclinT1 | p38 | TBK1 |
CDK2/CyclinA2 | CDK12/Cyclink | PLK1 | TNIK |
CDK2/CyclinE1 | cRAF | PIM1 | TTK(Msp1) |
Note: Not all targets will have a commercially available reference control. Please inquire with our team if you need to furnish your own controls for specific targets.
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