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BPS Bioscience的激酶筛选和检测服务

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    • BPS Bioscience

    • 服务名称:

      BPS Bioscience的激酶筛选和检测服务

    Accelerate your drug discovery program with Kinase Screening and Profiling Services from BPS Bioscience, Inc. Trust us to provide you with high quality data with fast turnaround time. Our team of experts along with our broad services portfolio makes it easy to:

      • Screen for inhibitors/targets using our unique panel of 75+ assays

      • Select from IC50 determination and single point concentrations

      • Receive data within days of compound submission

      • Perform follow-up studies using the same proteins manufactured in-house

      • Get questions answered or project guidance in a time-efficient manner

    图片Biochemical Assays

    Lipid:

    PI3Kα (p110α/p85α)PI3Kβ (p110β/p85α)PI3Kδ (p110δ/p85α)PI3Kγ (p110γ/PIK3R5)
    SPHK1   

     

    Tyrosine:

    Ablc-SrcFGFR3(V443M)PDGFRα
    Abl-1 (T315I)EGFR (WT)FGFR4PDGFRα(D842Y)
    ALKEGFR (L858R)Flt1RET
    ALK2EGFR (T790M)Flt3ROS1
    AXLEGFR (L858R, T790M)FYNSYK
    BTKEGFR(T790M, C797S,L858R)HER2TYK2
    cKIT(D816V)EGFR (murine)HER4TYRO3
    cKIT(V654A)EphA2Jak1VEGFR2/KDR
    cMetEphB4Jak2(JH2)Yes1
    cMet (exon 14 Del)FAKJak2(JH2)(V617F) 
    cMet (WT)FGFR2Jak3 
    cMerFGFR3(L496V)FGFR2 
    CSF1R(FMS)FGFR3(V443L)Lck 

    Serine-Threonine:

    AKTCDK4/CyclinD1GSK3aPIM2
    Aurora ACDK4/CyclinD3GSK3bPIM3
    BRAFCDK5/p25HPK1/MAP4K1RIPK1
    BRAF (V600E)CDK6/CyclinD3IKKβRIPK2
    Casein Kinase 1CDK7/CyclinH1/
    MNET1
    MNK1TAK1-TAB1
    CDK1/CyclinB1CDK9/CyclinT1p38TBK1
    CDK2/CyclinA2CDK12/CyclinkPLK1TNIK
    CDK2/CyclinE1cRAFPIM1TTK(Msp1)

     

    Note: Not all targets will have a commercially available reference control. Please inquire with our team if you need to furnish your own controls for specific targets.


    更多详情:

    http://www.bpsbioscience.com.cn/Products-37920558.html

    http://www.bpsbioscience.com.cn/Products-37920558.html

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